In summary, high speed PCB design requires deliberate thought and attention to detail. You should load the schematic with as much information as possible. Remember that where you put components on the the board is just as important as  where you put entire circuits. You should take the lead when laying out your board. Don't leave anything to chance. Make sure to use multiple capacitors for power supply bypassing. Parasitics must be considered and dealt with. Ground and power planes play a key role in reducing noise and parasitics. New packaging and pinouts allow for improved performance and more compact layouts. There are many options for signal distribution. Make sure you choose the right one for your application. Always check the layout very carefully.