Direct-to-Air assemblies offer dependable, compact performance by cooling objects via conduction. Heat is absorbed through a cold plate and thermoelectric cooler pumps heat through a hot side heat exchanger and into the ambient environment. The internal cold plate allows the chamber to be completely sealed, which aids in containing bio-hazardous liquids and minimizing contamination. It also saves space in small chambers that cannot accommodate a cold side heat exchanger. This configuration is commonly used in smaller sample storage chambers for medical and analytical instrumentation, spot cooling for laser systems or sensitive optical electronics used in the industrial and telecom markets.